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    Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)

    PAR-24-304

    National Institutes of Health

    Opening date 10 Oct 2024, 12:00AM

    Closing date 14 Oct 2026, 12:00AM

    Funding Opportunity Number: PAR-24-304

    Opportunity Category: Discretionary

    CFDA Number(s): 93.394 -- Cancer Detection and Diagnosis Research

    Cost Sharing or Matching Requirement: No

    Posted Date: Oct 10, 2024 12:00:00 AM EDT

    Closing Date: Oct 14, 2026 12:00:00 AM EDT

    Award Ceiling: none

    Award Floor: none

    Eligible Applicants: For profit organizations other than small businesses,Native American tribal organizations (other than Federally recognized tribal governments),Native American tribal governments (Federally recognized),Others (see text field entitled "Additional Information on Eligibility" for clarification),Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education,Public housing authorities/Indian housing authorities,Public and State controlled institutions of higher education,Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education,Private institutions of higher education,County governments,Special district governments,Small businesses,State governments,Independent school districts,City or township governments

    Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

    Agency Name: National Institutes of Health

    Description: Through this Notice of Funding Opportunity (NOFO) is to accelerate the pace of translation of NCI-supported methods/assays/technologies (referred to as "assays") to the clinic. Specifically, the focus of this NOFO is on the adaption and clinical validation of molecular/cellular/imaging markers (referred to as "markers" r "biomarkers") for cancer detection, diagnosis, prognosis, monitoring, and prediction of response in treatment, as well as markers for cancer control and prevention. Research applications may support the acquisition of well-annotated specimens from NCI-supported or other clinical trials or observational cohorts/consortia for the purpose of clinical validation of the assay. Research projects proposed for this NOFO encourage multi-disciplinary interaction among scientific investigators, assay developers, clinicians, statisticians, and clinical laboratory staff. Clinical laboratory scientist(s) and statistical experts are highly encouraged to comprise integral parts of the application. This NOFO is not intended to support early-stage development of technology or the conduct of clinical trials, but rather the adaption and validation of assays to the point where they could be integrated into clinical trials as investigational assays/tools/devices.

    Grantor Contact Information: NIH Grants Information grantsinfo@nih.gov

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