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    Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)

    PAR-24-047

    National Institutes of Health

    Opening date 10 Oct 2023, 12:00AM

    Closing date 13 Oct 2026, 12:00AM

    Funding Opportunity Number: PAR-24-047

    Opportunity Category: Discretionary

    CFDA Number(s): 93.394 -- Cancer Detection and Diagnosis Research

    Cost Sharing or Matching Requirement: No

    Posted Date: Oct 10, 2023 12:00:00 AM EDT

    Closing Date: Oct 13, 2026 12:00:00 AM EDT

    Award Ceiling: $150000

    Award Floor: none

    Eligible Applicants: City or township governments,For profit organizations other than small businesses,Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education,Native American tribal governments (Federally recognized),State governments,Small businesses,Others (see text field entitled "Additional Information on Eligibility" for clarification),Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education,Independent school districts,Public and State controlled institutions of higher education,County governments,Private institutions of higher education,Public housing authorities/Indian housing authorities,Special district governments,Native American tribal organizations (other than Federally recognized tribal governments)

    Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

    Agency Name: National Institutes of Health

    Description: Through this Notice of Funding Opportunity (NOFO) is to accelerate the pace of translation of NCI-supported methods/assays/technologies (referred to as "assays") to the clinic. Specifically, the focus of this NOFO is on the adaption and clinical validation of molecular/cellular/imaging markers (referred to as "markers" r "biomarkers") for cancer detection, diagnosis, prognosis, monitoring, and prediction of response in treatment, as well as markers for cancer control and prevention. Research applications may support the acquisition of well-annotated specimens from NCI-supported or other clinical trials or observational cohorts/consortia for the purpose of clinical validation of the assay. Research projects proposed for this NOFO encourage multi-disciplinary interaction among scientific investigators, assay developers, clinicians, statisticians, and clinical laboratory staff. Clinical laboratory scientist(s) and statistical experts are highly encouraged to comprise integral parts of the application. This NOFO is not intended to support early-stage development of technology or the conduct of clinical trials, but rather the adaption and validation of assays to the point where they could be integrated into clinical trials as investigational assays/tools/devices.

    Grantor Contact Information: NIH Grants Information grantsinfo@nih.gov

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