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    Country
    Opportunity Status
    Funding Instrument Type
    Category
    Clear

    Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)

    PAR-25-206

    National Institutes of Health

    Opening date 31 Oct 2024, 12:00AM

    Closing date 7 Jan 2028, 12:00AM

    Funding Opportunity Number: PAR-25-206

    Opportunity Category: Discretionary

    CFDA Number(s): 93.242 -- Mental Health Research Grants

    Cost Sharing or Matching Requirement: No

    Posted Date: Oct 31, 2024 12:00:00 AM EDT

    Closing Date: Jan 07, 2028 12:00:00 AM EST

    Award Ceiling: none

    Award Floor: none

    Eligible Applicants: Private institutions of higher education,Others (see text field entitled "Additional Information on Eligibility" for clarification),State governments,Public housing authorities/Indian housing authorities,Native American tribal organizations (other than Federally recognized tribal governments),Independent school districts,Public and State controlled institutions of higher education,Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education,County governments,For profit organizations other than small businesses,Small businesses,Special district governments,City or township governments,Native American tribal governments (Federally recognized),Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

    Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

    Agency Name: National Institutes of Health

    Description: NIMH seeks applications for pilot effectiveness projects to evaluate the preliminary effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions that are matched to the stage of illness in terms of both their focus (e.g., consolidating and maintaining gains from initial treatment, managing residual symptoms/impairment, preventing relapse, promoting adherence and appropriate service use) and intensity/burden. In this pilot phase of effectiveness research, the trial should be designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach; to address whether the intervention engages the target(s)/mechanisms(s) that is/are presumed to underlie the intervention effects; and to obtain preliminary data needed as a pre-requisite to a larger-scale effectiveness trial (e.g., comparative effectiveness study, practical trial) designed to definitely test the effectiveness of interventions to improve post-acute outcomes. This Notice of Funding Opportunity (NOFO) supports pilot effectiveness research to evaluate the feasibility, tolerability, acceptability, safety and preliminary indications of effectiveness of post-acute phase intervention approaches and inform the design of definitive effectiveness trials. Support for fully-powered, definitive effectiveness studies focused on post-acute phase interventions is provided via the R01 currently TEMP-24813.

    Grantor Contact Information: NIH Grants Information grantsinfo@nih.gov

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