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    Country
    Opportunity Status
    Funding Instrument Type
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    Clear

    Neuropathological Interactions Between COVID-19 and ADRD (R01 - Clinical Trial Not Allowed)

    PAR-24-203

    National Institutes of Health

    Opening date 12 Apr 2024, 12:00AM

    Closing date 4 Oct 2024, 12:00AM

    Funding Opportunity Number: PAR-24-203

    Opportunity Category: Discretionary

    CFDA Number(s): 93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders,93.866 -- Aging Research

    Cost Sharing or Matching Requirement: No

    Posted Date: Apr 12, 2024 12:00:00 AM EDT

    Closing Date: Oct 04, 2024 12:00:00 AM EDT

    Award Ceiling: $500000

    Award Floor: none

    Eligible Applicants: Native American tribal organizations (other than Federally recognized tribal governments),Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education,Small businesses,Private institutions of higher education,Independent school districts,Public and State controlled institutions of higher education,Public housing authorities/Indian housing authorities,State governments,Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education,Special district governments,For profit organizations other than small businesses,Native American tribal governments (Federally recognized),County governments,City or township governments,Others (see text field entitled "Additional Information on Eligibility" for clarification)

    Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

    Agency Name: National Institutes of Health

    Description: This NOFO will solicit R01 applications that propose studies in animal, cell culture, and/or human tissue models to elucidate the mechanisms by which COVID-19 interacts with and/or modulates AD/ADRD-relevant phenotypes. Either the model itself or the experimental readouts will be required to incorporate AD/ADRD risk factors, pathologies, or relevant comorbidities. To this end, proposals can focus on one or more of the following: - Mechanistic studies that address how COVID-19 impacts CNS pathology and cognitive outcomes when AD/ADRD pathology is already present (for example, in a model of AD/ADRD). - Mechanistic studies that address how COVID-19 accelerates AD/ADRD pathology and cognitive deficits in a prodromal model (early phase, pre-symptomatic). - Mechanistic studies that address how COVID-19 predisposes for AD/ADRD and/or interacts with relevant comorbid conditions and risk factors (cellular mechanisms that could potentially increase the risk for future AD/ADRD).

    Grantor Contact Information: NIH Grants Information grantsinfo@nih.gov

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