Value AD
CAN BE
ALTERNATIVE
INVESTMENT
Natural History of Disorders Screenable in the Newborn Period (R01 Clinical Trial Optional)
PAR-21-115
National Institutes of Health
Funding Opportunity Number: PAR-21-115
Opportunity Category: Discretionary
CFDA Number(s): 93.865 -- Child Health and Human Development Extramural Research
Cost Sharing or Matching Requirement: No
Posted Date: Feb 08, 2021 12:00:00 AM EST
Closing Date: Jan 07, 2024 12:00:00 AM EST
Award Ceiling: none
Award Floor: none
Eligible Applicants: Special district governments,State governments,Native American tribal governments (Federally recognized),Public and State controlled institutions of higher education,Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education,Public housing authorities/Indian housing authorities,Native American tribal organizations (other than Federally recognized tribal governments),For profit organizations other than small businesses,City or township governments,Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education,Private institutions of higher education,Others (see text field entitled "Additional Information on Eligibility" for clarification),County governments,Independent school districts,Small businesses
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Agency Name: National Institutes of Health
Description:
This funding opportunity announcement (FOA) encourages applications that propose to develop studies that will lead to a broad understanding of the natural history of disorders that already do or could potentially benefit from early identification by newborn screening. A comprehensive understanding of the natural history of a disorder has been identified as a necessary element to facilitate appropriate interventions for infants identified by newborn screening. By defining the sequence and timing of the onset of symptoms and complications of a disorder, a valuable resource will be developed for the field. In addition, for some disorders, specific genotype-phenotype correlations may allow prediction of the clinical course, and for other disorders, identification of modifying genetic, epigenetic, or environmental factors will enhance an understanding of the clinical outcomes for an individual with such a condition. Comprehensive data on natural history will facilitate the field's ability to: 1) accurately diagnose the disorder; 2) understand the genetic and clinical heterogeneity and phenotypic expression of the disorder; 3) identify underlying mechanisms related to basic defects; 4) potentially prevent, manage, and treat symptoms and complications of the disorder; and 5) provide children and their families with needed support and predictive information about the disorder.
Grantor Contact Information: NIH OER Webmaster FBOWebmaster@OD.NIH.GOV
