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    Country
    Opportunity Status
    Funding Instrument Type
    Category
    Clear

    Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R21 Clinical Trial Not Allowed)

    PAR-22-086

    National Institutes of Health

    Opening date 18 Feb 2022, 12:00AM

    Closing date 7 May 2025, 12:00AM

    Funding Opportunity Number: PAR-22-086

    Opportunity Category: Discretionary

    CFDA Number(s): 93.121 -- Oral Diseases and Disorders Research,93.395 -- Cancer Treatment Research,93.396 -- Cancer Biology Research

    Cost Sharing or Matching Requirement: No

    Posted Date: Feb 18, 2022 12:00:00 AM EST

    Closing Date: May 07, 2025 12:00:00 AM EDT

    Award Ceiling: $200000

    Award Floor: none

    Eligible Applicants: County governments,Native American tribal governments (Federally recognized),City or township governments,Independent school districts,Special district governments,Others (see text field entitled "Additional Information on Eligibility" for clarification),Private institutions of higher education,Small businesses,Native American tribal organizations (other than Federally recognized tribal governments),Public housing authorities/Indian housing authorities,State governments,For profit organizations other than small businesses,Public and State controlled institutions of higher education,Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education,Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

    Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

    Agency Name: National Institutes of Health

    Description: This Funding Opportunity Announcement (FOA) solicits grant applications proposing to utilize bacteria, archaebacteria, bacteriophages, or other non-oncolytic viruses and their natural products to study the underlying mechanisms of the complex interactions between microorganisms, tumors, and the immune system, and to explore their clinical potential for cancer imaging, therapeutics or diagnostics. Projects can focus on using microorganisms as anti-tumor agents, as activators of anti-tumor immunity, or as delivery vehicles for treatment, diagnosis, or imaging, complementing or synergizing with existing tools and approaches. This FOA will support basic mechanistic and preclinical studies in cell culture and animal models. Applicants are encouraged to address both the microbial and tumor aspects of microbial tumor interactions relevant to microbial-based cancer therapy (including therapies for oral cancer), tumor imaging, tumor detection, or diagnosis. The R21 FOA is intended to encourage exploratory projects that are at an early conceptual stage feasibility study (inception through preliminary development) to demonstrate the core functional capabilities of the proposed approach. The proposed projects may involve considerable risk and should be aimed at producing breakthroughs in microbial-based cancer therapy, imaging, or diagnosis. This funding opportunity is part of broader NCI-sponsored research on microbial-based cancer therapy.

    Grantor Contact Information: NIH OER Webmaster OERWebmaster03@od.nih.gov

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