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    Forecast to Publish a Notice of Funding Opportunity (NOFO) for NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required)

    NOT-CA-25-042

    Brandy Heckman-Stoddard, Ph.D., M.P.H. National Cancer Institute (NCI)

    Opening date 28 May 2025, 12:00AM

    Closing date N/A

    Funding Opportunity Number: NOT-CA-25-042

    Opportunity Category: Discretionary

    Expected Number of Awards: 7

    CFDA Number(s): 93.399 -- Cancer Control

    Cost Sharing or Matching Requirement: No

    Posted Date: May 28, 2025 12:00:00 AM EDT

    Closing Date: N/A

    Estimated Total Program Funding: 60000000

    Eligible Applicants: For profit organizations other than small businesses,Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education,Private institutions of higher education,County governments,Native American tribal organizations (other than Federally recognized tribal governments),State governments,Small businesses,Native American tribal governments (Federally recognized),Public and State controlled institutions of higher education

    Description:

    This Notice of Funding Opportunity (NOFO) is one of three NOFOs for the National Cancer Institute (NCI) Community Oncology Research Program (NCORP). NCORP is designed to enhance generalizability and dissemination of clinical trial results through accrual in a variety of community settings. The purpose of NCORP is to engage cancer patient populations, those at risk of cancer, and organizations in rigorous studies focused on cancer control, prevention, treatment and care delivery.


    NCORP will support the following components that will be individually awarded through the respective Request for Applications (RFAs) indicated below:

    • NCORP Research Bases (UG1 Clinical Trials Required);
    • NCORP Community Sites (UG1 Clinical Trials Not Allowed); and
    • NCORP Academic Community Sites (UG1 Clinical Trials Not Allowed) 


    NCORP Research Bases will serve as research hubs for the NCORP network. Research Bases are expected to:

    • Provide an established organizational structure, with scientific and statistical leadership for developing, implementing, and analyzing multi-institutional cancer control, prevention, and care delivery (CCP&CD) clinical research, as well as quality-of-life studies embedded within treatment and imaging studies.
    • Assume responsibility for study operations and data management, including efficient protocol development, compliance with Food and Drug Administration (FDA) and Office of Human Research Protections (OHRP) regulatory and participant protection requirements, audits, training, quality assurance, and support to Community Sites and Minority/Underserved Community Sites.
    • Conduct their research activities at an institution with comprehensive expertise in cancer clinical research, such as a cancer foundation, healthcare research organization (including NCI's National Clinical Trials Network Group Operations Centers), or NCI-designated Cancer Center.
    • Integrate health disparities across all focus areas as appropriate.

    The scope of research activities for the proposed NCORP Research Bases encompasses three major areas delineated below:

    Area 1: Cancer Control Research; and/or

    Area 2: Cancer Prevention Research; and

    Area 3: Cancer Care Delivery Research.

    Research Bases must cover Area 1. Areas 2 and 3 are optional. 

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