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    Opportunity Status
    Funding Instrument Type
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    Clear

    Development and Validation of Human Cellular Models for Alzheimer's Disease-Related Dementias (ADRD) (R01 - Clinical Trial Not Allowed)

    RFA-NS-24-032

    National Institutes of Health

    Opening date 16 Feb 2024, 12:00AM

    Closing date 21 Oct 2024, 12:00AM

    Funding Opportunity Number: RFA-NS-24-032

    Opportunity Category: Discretionary

    CFDA Number(s): 93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders,93.866 -- Aging Research

    Cost Sharing or Matching Requirement: No

    Posted Date: Feb 16, 2024 12:00:00 AM EST

    Closing Date: Oct 21, 2024 12:00:00 AM EDT

    Award Ceiling: $500000

    Award Floor: none

    Eligible Applicants: County governments,Others (see text field entitled "Additional Information on Eligibility" for clarification),Public housing authorities/Indian housing authorities,Independent school districts,State governments,City or township governments,Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education,For profit organizations other than small businesses,Native American tribal governments (Federally recognized),Native American tribal organizations (other than Federally recognized tribal governments),Private institutions of higher education,Small businesses,Special district governments,Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education,Public and State controlled institutions of higher education

    Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

    Agency Name: National Institutes of Health

    Description: This NOFO would support development and validation of novel clinically- and/or pathophysiologically-relevant human cellular models of ADRD. The cellular model systems would be expected to capture the multi-faceted pathologies and multiple cell types observed in ADRDs. Validation includes internal, face, construct, and predictive (to the extent possible) validation. These models can be developed/validated with the goal of supporting therapy development or better understanding of human disease mechanisms and mechanisms that uncover predisposition to developing neurodegenerative dementias. Human cellular models need to be novel, complex, and address a gap in the currently available models. Multidisciplinary teams will be highly encouraged. Leveraging the use of and depositing new cells into existing NIH cell repository resources will also be encouraged.

    Grantor Contact Information: NIH Grants Information grantsinfo@nih.gov

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