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    ClinGen Genomic Curation Expert Panels (U24 Clinical Trial Not Allowed)

    PAR-23-199

    National Institutes of Health

    Opening date 6 Jun 2023, 12:00AM

    Closing date 25 May 2025, 12:00AM

    Funding Opportunity Number: PAR-23-199

    Opportunity Category: Discretionary

    CFDA Number(s): 93.173 -- Research Related to Deafness and Communication Disorders,93.350 -- National Center for Advancing Translational Sciences,93.399 -- Cancer Control,93.846 -- Arthritis, Musculoskeletal and Skin Diseases Research,93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders,93.865 -- Child Health and Human Development Extramural Research,93.867 -- Vision Research

    Cost Sharing or Matching Requirement: No

    Posted Date: Jun 06, 2023 12:00:00 AM EDT

    Closing Date: May 25, 2025 12:00:00 AM EDT

    Award Ceiling: $220000

    Award Floor: none

    Eligible Applicants: For profit organizations other than small businesses,County governments,Special district governments,Small businesses,Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education,Native American tribal governments (Federally recognized),Others (see text field entitled "Additional Information on Eligibility" for clarification),Private institutions of higher education,State governments,Public housing authorities/Indian housing authorities,City or township governments,Native American tribal organizations (other than Federally recognized tribal governments),Independent school districts,Public and State controlled institutions of higher education,Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

    Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

    Agency Name: National Institutes of Health

    Description: NIH established a clinical genomics infrastructure to develop an openly accessible knowledgebase that promotes data sharing and provides standardized infrastructure and tools for determining the clinical relevance of genetic variants through two initiatives: the Clinical Genomics Resource (ClinGen) and the Clinical Variant Database (ClinVar) of clinical variation. ClinGen defines the clinical relevance of genes and variants for use in precision medicine and research by standardizing clinical annotation and interpretation of variants and implementing evidence-based expert consensus assertions. The purpose of this Notice of Funding Opportunity (NOFO) is to establish Expert Panels that will select genes and genomic variants associated with diseases or conditions of high priority to participating NIH Institutes and Centers (ICs) and systematically determine their clinical significance for diagnosis and treatment of these diseases or conditions. The Genomic Curation Expert Panels funded through this NOFO are required to utilize the NHGRI Clinical Genomics Resource (ClinGen) and the NCBI ClinVar procedures, interfaces, tools, and informatics infrastructure.

    Grantor Contact Information: NIH Grants Information grantsinfo@nih.gov

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