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    Cellular Senescence Network (SenNet):Technology Projects (UG3/UH3 Clinical Trial Not Allowed)

    NOT-RM-25-018

    Ajay Pillai Office of Strategic Coordination, DPCPSI, OD

    Opening date 28 May 2025, 12:00AM

    Closing date N/A

    Funding Opportunity Number: NOT-RM-25-018

    Opportunity Category: Discretionary

    Expected Number of Awards: 15

    CFDA Number(s): 93.310 -- Trans-NIH Research Support

    Cost Sharing or Matching Requirement: No

    Posted Date: May 28, 2025 12:00:00 AM EDT

    Closing Date: N/A

    Estimated Total Program Funding: 6000000

    Eligible Applicants: Native American tribal governments (Federally recognized),Public housing authorities/Indian housing authorities,For profit organizations other than small businesses,Independent school districts,County governments,Native American tribal organizations (other than Federally recognized tribal governments),Private institutions of higher education,Small businesses,State governments,Public and State controlled institutions of higher education,Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

    Description:

    The NIH Common Fund, National Institute on Aging, National Cancer Institute and additional NIH Institutes and Centers (ICs) intend to publish a Notice of Funding Opportunity (NOFO) to solicit applications for Stage 2 of the Cellular Senescence Network (SenNet) Program, which seeks to understand the biological consequences of senescent cell heterogeneity in health and disease, identify and characterize tissue-specific senescence markers in human biospecimens to facilitate the development of senotherapeutic strategies that improve health outcomes. The program’s Senescence Technology Projects (SenTecs) will develop innovative tools and technologies that consider the complex nature of senescence to facilitate identification, characterization and targeting of senotypes in vivo. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the UG3/UH3 activity code. Investigators with expertise and insights into the cellular senescence impact on human health, the development of technologies and computational tools to identify and characterize senescent cells and inform novel approaches for the strategic targeting of senescent cells in vivo are encouraged to apply in response to these new NOFOs.

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