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    Country
    Opportunity Status
    Funding Instrument Type
    Category
    Clear

    BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)

    RFA-NS-24-005

    National Institutes of Health

    Opening date 14 Mar 2023, 12:00AM

    Closing date 20 Jan 2026, 12:00AM

    Funding Opportunity Number: RFA-NS-24-005

    Opportunity Category: Discretionary

    CFDA Number(s): 93.173 -- Research Related to Deafness and Communication Disorders,93.213 -- Research and Training in Complementary and Integrative Health,93.242 -- Mental Health Research Grants,93.273 -- Alcohol Research Programs,93.279 -- Drug Abuse and Addiction Research Programs,93.286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health,93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders,93.865 -- Child Health and Human Development Extramural Research,93.866 -- Aging Research,93.867 -- Vision Research

    Cost Sharing or Matching Requirement: No

    Posted Date: Mar 14, 2023 12:00:00 AM EDT

    Closing Date: Jan 20, 2026 12:00:00 AM EST

    Award Ceiling: none

    Award Floor: none

    Eligible Applicants: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education,Public and State controlled institutions of higher education,Native American tribal organizations (other than Federally recognized tribal governments),Small businesses,County governments,City or township governments,Private institutions of higher education,For profit organizations other than small businesses,State governments,Special district governments,Independent school districts,Native American tribal governments (Federally recognized),Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education,Others (see text field entitled "Additional Information on Eligibility" for clarification),Public housing authorities/Indian housing authorities

    Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

    Agency Name: National Institutes of Health

    Description: Reissue of RFA-NS-18-019: Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. The invention, proof-of-concept investigation, and optimization of new technologies through iterative feedback from end users are key components of the BRAIN Initiative. This FOA seeks applications to optimize existing or emerging technologies through iterative testing with end users. The technologies and approaches should have potential to address major challenges associated with recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS). These technologies and approaches should have previously demonstrated their transformative potential through initial proof-of-concept testing and are now ready for accelerated refinement. In conjunction, the manufacturing techniques should be scalable towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience research.Proposed technologies should be compatible with experiments in behaving animals, validated under in vivo experimental conditions, and capable of reducing major barriers to conducting neurobiological experiments and making new discoveries about the CNS. Technologies may engage diverse types of signaling beyond neuronal electrical activity such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. If suitable, applications are expected to integrate appropriate domains of expertise, including biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

    Grantor Contact Information: NIH Grants Information grantsinfo@nih.gov

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