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    Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

    PAR-21-163

    National Institutes of Health

    Opening date 11 Mar 2021, 12:00AM

    Closing date 7 May 2024, 12:00AM

    Funding Opportunity Number: PAR-21-163

    Opportunity Category: Discretionary

    CFDA Number(s): 93.121 -- Oral Diseases and Disorders Research,93.213 -- Research and Training in Complementary and Integrative Health,93.242 -- Mental Health Research Grants,93.273 -- Alcohol Research Programs,93.279 -- Drug Abuse and Addiction Research Programs,93.286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health,93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders,93.865 -- Child Health and Human Development Extramural Research,93.866 -- Aging Research,93.867 -- Vision Research

    Cost Sharing or Matching Requirement: No

    Posted Date: Mar 11, 2021 12:00:00 AM EST

    Closing Date: May 07, 2024 12:00:00 AM EDT

    Award Ceiling: none

    Award Floor: none

    Eligible Applicants: Native American tribal governments (Federally recognized),Public housing authorities/Indian housing authorities,Private institutions of higher education,For profit organizations other than small businesses,City or township governments,State governments,Native American tribal organizations (other than Federally recognized tribal governments),Others (see text field entitled "Additional Information on Eligibility" for clarification),Public and State controlled institutions of higher education,Independent school districts,Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education,Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education,County governments,Small businesses,Special district governments

    Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

    Agency Name: National Institutes of Health

    Description:

    The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. This Funding Opportunity Announcement (FOA) supports preclinical discovery and development of potential therapeutic Biotechnology Products and Biologics including, but not limited to, large biologic macromolecules, (e.g., proteins, antibodies, and peptides), gene-based therapies (i.e., oligonucleotide- and viral-based), cell therapies, and novel emerging therapies (e.g., microbial and microbiome therapies). Applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in manufacturing, scaling, pharmacokinetics, toxicology, and Phase I clinical testing. BPN-Biologics awardee institutions retain their assignment of IP rights and gain assignment of IP rights from the BPN-Biologics contractors (and thereby control the patent prosecution and licensing negotiations) for biotherapeutic candidates developed in this program.

    Grantor Contact Information: NIH OER Webmaster FBOWebmaster@OD.NIH.GOV

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